منابع مشابه
The mechanism of acetoacetate synthesis.
The observation of a coenayme A (CoA)-catalyzed acetoacetate synthesis from acetate and adenosinetriphosphate in pigeon liver extracts (1) grouped this reaction with the larger family of acetylation reactions. Furthermore it furnished partial confirmation of an earlier calculation (2) showing that 16,000 calories are required for the condensation of two acetates to acetoacetate. Thus, one energ...
متن کاملcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولOn the mechanism of acetoacetate synthesis by guinea pig liver fractions.
1. Commercially available coenzyme A preparations were found to contain sufficient amounts of glutathione so that in the reaction with diketene significant quanties of acetoacetyl glutathione were formed. Unless allowances are made for this, significant errors in the interpretation of results can be made because liver mitochondria contain a very active acetoacetyl glutathione hydrolase. 2. Puri...
متن کاملSynthesis of acetoacetate by liver enzymes.
Two mechanisms have been proposed for the formation of acetoacetate from acetyl-CoA by liver preparations. With the use of a partially purified system prepared from acetone powders of beef liver, Lynen et al. (1) obtained evidence that acetoacetate formation proceeded via P-hydroxy-fi-methylglutaryl coensyme A as intermediate and involved the HlMG-COAT condensing and HMG-Coh cleavage enzymes as...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1951
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)50987-x